Barcelona forward Lionel Messi and Atletico Madrid striker Radamel Falcao were unstoppable Sunday on a memorable night when both stars again demonstrated why their teams fill the top two spots in the Spanish league.

Messi broke a 40-year record for most goals in a year by scoring his 85th and 86th goals of 2012 to lead Barcelona to a 2-1 win at Real Betis, while Falcao struck five times as Atletico thrashed Deportivo La Coruna 6-0.

Defending champion Juventus celebrated coach Antonio Conte's return with a win, beating Palermo 1-0 in Serie A on Sunday.

Stephan Lichtsteiner scored five minutes into the second half for Juventus, which also hit the goal-frame twice through Mirko Vucinic.

Robin van Persie scored a stoppage-time winner to give Manchester United a 3-2 win at Manchester City on Sunday, ending the champion's unbeaten start to the Premier League season and taking his side six points clear atop the standings.

Wayne Rooney had set United on the way to avenging last season's double derby defeat to City by scoring twice in the first half against the run of play.

Mexico's Juan Manuel Marquez knocked Manny Pacquiao out cold with a vicious right hand at the end of the sixth round Saturday, putting a sudden end to the fourth fight between the two boxers.

Pacquiao had been down in the third round but knocked Marquez down in the fifth and the two were exchanging heavy blows in the sixth round before Marquez threw a right hand that flattened Pacquiao face down on the canvas at 2:59 of the sixth round.

The Memphis Grizzlies lost their grip on the NBA's best record, sliding to third overall after Saturday's 93-83 home defeat at the hands of the Atlanta Hawks.

The San Antonio Spurs took over top spot with a win over Charlotte, while the New York Knicks' lead in the Eastern Conference was cut to one game after they lost at Chicago.

In the Rio de Janeiro suburb of Curicica, teenagers hold hands in pairs during a kickabout. But rather than scoring goals, team-work is the name of the game in this football match -- and finding jobs.

"It's not a football academy," said Heloisa Andrade, director of the "Partners of the Americas" institute, a Washington-based non-governmental organization founded in 1964, initially as part of the U.S. government.

Mesut Ozil grabbed two goals as Real Madrid twice came from behind to defeat Valladolid 3-2 on Saturday to close to within eight points of Barcelona at the top of La Liga.

The German international's brace included an exquisitely-curled, left-footed winner from a free-kick on 71 minutes to keep Madrid on the tails of Barca and second-placed Atletico Madrid.

Arsenal manager Arsene Wenger has confirmed he will review his side's opening penalty in the 2-0 win against West Bromwich Albion and speak to Santi Cazorla if he believes the Spaniard dived.

Cazorla went over in the 26th minute at the Emirates Stadium on Saturday despite replays suggesting he was not touched by Steven Reid.

Feng Shanshan came into the the 500,000 euros Dubai Ladies Masters as the highest ranked player in the field and she proved her credentials with an emphatic five-shot victory in the season-ending championship of the Ladies European Tour.

At the par-72 Majlis course of Emirates Golf Club, the world No.6 produced her worst round of the tournament - a three-under par 69 - but that was good enough to beat the second placed Dewi Claire Schreefel of Netherlands.

Opposing managers Roberto Mancini and Alex Ferguson have started sparring well before Sunday's Manchester derby after an exchange of barbs about penalties.

In Friday's pre-match press conference, Manchester United manager Ferguson suggested there would have been "an inquiry in the House of Commons" if his club had been awarded as many spot-kicks as Manchester City in recent years.